ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo
Chromatin endogenous cleavage (ChEC) uses fusion of a protein of interest to micrococcal nuclease (MNase) to target calcium-dependent cleavage to specific genomic loci in vivo. Here we report the ...
Morning Overview on MSN
DNA shape and stiffness steer key gene regulators
For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new wave of research is forcing a rethink, showing that the three-dimensional ...
Looking for a challenging and stimulating activity? Try solving a pattern-based puzzle posted on Instagram by Optical Illusions. The puzzle presents three patterns and asks you to predict the next ...
Introduce children to patterns, and help them learn to recognise the mathematical rules behind them, describe patterns and create their own, with these ideas from Sheila Ebbutt and Carole Skinner ...
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